Radiomics characterizes the tumor’s phenotype by extracting large number of quantitative image features from radiological images.  At the WU-C2IR2, we will use radiomic pipelines to phenotype preclinical and clinical PET and MR tumor image datasets.  Radiomic pipelines will be standardized and implemented in the context of co-clinical trials for the multi-parametric PET/MR imaging protocols listed in Table 1.

Table 1: Multi-parametric PET/MR Protocol
Dynamic (70min) FDG-PET (10mCi) imaging in parallel with MR sequences below
T1/T2 mapping
DTI (multi-shell)
Research DCE protocol—high temporal, low spatial resolution